Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
All Product Categories
-
Isotope-Labeled Compounds Related Products (11047)
Related Products (11047)
-
N-Myristoylglycine-d2-1
0 ImagesCat. No.: HY-W074889S1CAS No.: 3008541-81-6N-Myristoylglycine-d2-1 is the deuterium labeled N-Myristoylglycine (HY-W074889). N-Myristoylglycine is a glycine derivative.
-
[1,1'-Biphenyl]-4-ol-d9
![[1,1'-Biphenyl]-4-ol-d9](https://file.medchemexpress.com/product_pic/hy-y0162s1.gif "Click to View [1,1'-Biphenyl]-4-ol-d9 Product Detail")
0 Images[1,1'-Biphenyl]-4-ol-d9 is the deuterium labeled [1,1'-Biphenyl]-4-ol.
-
Oxybenzone-13C6
0 ImagesCat. No.: HY-A0067S1Synonyms: Benzophenone 3-13C6Oxybenzone-13C6 (Benzophenone 3-13C6) is the 13C-labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells.
-
Nicergoline-13C,d3
0 ImagesCat. No.: HY-B0702SNicergoline-13C,d3 is the 13C- and deuterium labeled Nicergoline. Nicergoline, an ergoline derivative ester of bromonicotinic acid, is a potent, selective and orally active antagonist of α1A-adrenoceptor. Nicergoline has vasodilator effects. Nicergoline also has ameliorative effects on cognitive function in mouse models of Alzheimer's disease.
-
Gusacitinib-d4
0 ImagesCat. No.: HY-103018SSynonyms: ASN-002-d4Gusacitinib-d4 (ASN-002-d4) is the deuterium labeled Gusacitinib (HY-103018). Gusacitinib (ASN-002) is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively. Gusacitinib rapidly and significantly suppressed key inflammatory pathways implicated in atopic dermatitis pathogenesis. Gusacitinib can be used in the research of chronic hand eczema and cancers such as basal cell carcinoma.
-
rac 1,2-Bis-palmitoyl-3-chloropropanediol-13C3
0 ImagesCat. No.: HY-W653931rac 1,2-Bis-palmitoyl-3-chloropropanediol-13C3 is the 13C-labeled
-
(Rac)-Talinolol-d5
0 ImagesCat. No.: HY-108286SCAS No.: 1215343-94-4(Rac)-Talinolol-d5 is the racemate of Talinolol. Talinolol (Cordanum) is a long-acting, cardioselective β1-adrenergic receptor blocker. Talinolol exhibits cardioprotective and antihypertensive activities. Talinolol is also a well-known and frequently used probe substrate for P-glycoprotein (P-gp) activity.
-
Azoxystrobin-d4
0 ImagesCat. No.: HY-B0849SCAS No.: 1346606-39-0Azoxystrobin-d4 is deuterium labeled Azoxystrobin. Azoxystrobin is a broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
-
1-Methylimidazole-d3-1
0 ImagesCat. No.: HY-59137S2CAS No.: 4166-68-11-Methylimidazole-d3-1 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
-
Gartisertib-d8
0 ImagesCat. No.: HY-136270SCAS No.: 1792214-00-6Synonyms: VX-803-d8; M4344-d8; ATR inhibitor 2-d8Gartisertib-d8 (VX-803-d8) is the deuterium labeled Gartisertib (HY-136270). Gartisertib (VX-803) is an ATP-competitive, orally active, and selective ATR inhibitor, with a Ki of <150 pM. Gartisertib potently inhibits ATR-driven phosphorylated checkpoint kinase-1 (Chk1) phosphorylation with an IC50 of 8 nM. Antitumor activity.
-
Valproic acid methyl ester-d3
0 ImagesCat. No.: HY-W587840SValproic acid methyl ester-d3 is the deuterium labeled Valproic acid methyl ester.
-
Lodoxamide impurity 2-d10
0 ImagesCat. No.: HY-W270557SLodoxamide impurity 2-d10 is deuterium labeled 2-(Diethylamino)-2-oxoacetic acid.
-
Vonoprazan-d3 fumarate
0 ImagesCat. No.: HY-Z3421SVonoprazan-d3 fumarate is the deuterium labeled Vonoprazan fumarate (HY-15295). Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan Fumarate inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease.
-
Flibanserin-d4-1
0 ImagesSynonyms: BIMT-17-d4-1; BIMT-17BS-d4-1Flibanserin-d4-1 (BIMT-17-d4-1; BIMT-17BS-d4-1) is the d4-labeled Flibanserin (HY-A0095). Flibanserin is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki values of 1 nM and 49 nM, respectively. Flibanserin binds to dopamine D4 receptors with an Ki value of 4-24 nM. Flibanserin shows anti-depression and anti-anxiety effect, can be used to hypoactive sexual desire disorder (HSDD) research-.
-
Methyl carbamimidothioate sulfate-13C
0 ImagesCat. No.: HY-W751109CAS No.: 2729938-56-9Methyl carbamimidothioate sulfate-13C is the 13C-labeled Methyl carbamimidothioate sulfate (HY-W089554).
-
Fmoc-Cys(Trt)-OH-1,2,3-13C3,15N
0 ImagesFmoc-Cys(Trt)-OH-1,2,3-13C3,15N is a 15N-labeled and 13C-labled Fmoc-Cys(Trt)-OH-1,2,3 (HY-W007798). Fmoc-Cys(Trt)-OH is a cysteine derivative.
-
1,4-Bis(7-chloroquinolin-4-yl)piperazine-d8
0 ImagesCat. No.: HY-W7515231,4-Bis(7-chloroquinolin-4-yl)piperazine-d8 is the deuterium labeled 1,4-Bis(7-chloroquinolin-4-yl)piperazine (HY-W103104).
